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AssigneeRiken Vitamin Co., Ltd.
InventorsMinoru Sato, MinoruTakashi Ooba, Akio Kobayashi, Katsura Funayama, Takashi Kahara, Takahisa Nakano
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The subject of the invention is to produce a peptide with potent the angiotensin I-converting enzyme (ACE) inhibitory activity by decomposing the protein contained in wakame with protease, using wakame being a food material ingested daily as a raw material, and to provide a safe food composition with hypotensive activity, using the treatment product thereof as a raw material. The inventors have found that, when performing the decomposing treatment of wakame with various proteases, a group of endo-type enzymes produced by Bacillus produce peptides with particularly strong ACE inhibitory activity, leading to the completion of the invention.
An angiotensin I-converting enzyme inhibitory substance, containing peptide obtained by decomposing wakame with protease other than pepsin.
A decomposition conduct of protein with blood-pressure lowering activity characterized by containing a peptide with potent an angiotensin I-converting enzyme inhibitory activity wherein said peptide is obtained by decomposing wakame with a protease other than pepsin.
A preparing method of an angiotensin I-converting enzyme inhibitory substance, characterized by decomposing wakame with protease other than pepsin to give a peptide with potent an angiotensin I-converting enzyme inhibitory activity.
Dependencies are inferred from the claim text.