Mammalian alpha helical protein-1
AssigneeZymoGenetics, Inc.
InventorsSi Lok, Darrell C. Conklin, Julia E. Parrish
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Abstract
Novel mammalian alpha helical polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods including antibodies and anti-idiotypic antibodies.
Claims10
An isolated polynucleotide which encodes a mammalian polypeptide, said polypeptide being comprised of amino acid sequence defined by SEQ ID NO:45 or an amino acid sequence which is at least 90% identical to SEQ ID NO:45.
A vector comprising the following operably linked elements:
- a transcription promoter;
- a DNA segment encoding a mammalian polypeptide, said polypeptide being comprised of amino acid sequence defined by SEQ ID NO:45
- a transcription terminator.
An isolated polypeptide comprised of a mammalian polypeptide, said polypeptide being comprised of an amino acid sequence defined by SEQ ID NO:45 or a polypeptide which is at least 90% identical to SEQ ID NO:45.
A polypeptide according to claim 6 further comprising a second polypeptide or protein.
An antibody that specifically binds to a mammalian polypeptide, said polypeptide being comprised of SEQ ID NO:45 or polypeptide which is at least 90% identical to SEQ ID NO:45.
An anti-idiotypic antibody of an antibody which specifically binds to a mammalian polypeptide said mammalian polypeptide being comprised of SEQ ID NO:45 or a polypeptide which is at least 90% identical to SEQ ID NO:45.
A polypeptide which contains an amino acid sequence of an epitope-bearing portion of SEQ ID NO:45, said epitope-bearing portion having at least 30 amino acid residues of SEQ ID NO:45.
Dependencies are inferred from the claim text.