Forms of prostate specific antigens and methods for their detection
AssigneeHybritech Incorporated
InventorsStephen D. Mikolajczyk, Harry G. Rittenhouse, Abhay Kumar, Mohammad S. Saedi, Robert L. Wolfert
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Abstract
Inactive precursor forms of PSA (pPSA) have been identified to exist in serum and tissues of patients with prostate cancer. Antibodies specific for pPSA are provided. Methods for detecting inactive precursors of PSA in human physiological fluid and tissues are also provided, as well as diagnostic kits and methods useful in the diagnosis and management of prostate cancer.
Claims24
An antibody that specifically binds to a pPSA.
A hybridoma cell line producing an antibody that specifically binds to pPSA.
A diagnostic kit for detecting or determining pPSA in a sample comprising a known amount of an antibody that specifically binds to pPSA.
Dependencies are inferred from the claim text.