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US 2002/0058060 A1Published application
Liposome for incorporating large amounts of hydrophobic substances
OwnerPei Kan, Ae-June Wang +2inventors
InventorsPei Kan, Ae-June Wang, Won-Ko Chen, Chih-Wan Tsao
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Abstract
A liposome for stably incorporating high content of hydrophobic substance is disclosed. The liposome includes two phospholipids with different phase transition temperatures such as saturated and unsaturated phosphatidyl cholines, hydrophobic substances, cholesterol, cholesterol derivatives, antioxidant and hydrophilic polymer-modified lipids such as MPEG-DSPE.
Claims36
A liposome for incorporating high content of hydrophobic substances comprising:
- a first phospholipid;
- a second phospholipid;
- one or more hydrophobic substances;
- and
- liposome-forming materials, wherein the first and the second phospholipid coexist in the liposome in a separated-phase form.
2 more elements
A liposome for incorporating high content of hydrophobic substances comprising:
- a first phosphatidyl choline;
- a second phosphatidyl choline;
- one or more hydrophobic substances;
- and
- liposome-forming materials, wherein the first and the second phosphatidyl cholines coexist in the liposome in a separated-phase form.
2 more elements
Dependencies are inferred from the claim text.