Brachytherapy seed
AssigneeMicrospherix LLC
InventorEdward J. Kaplan
Life of this patent
Estimating the term…
Abstract
A radiopaque brachytherapy seed for implantation into a subject includes a biocompatible component, a therapeutically active component including a non-radioactive drug, and a radiopaque marker. The biocompatible component is (a) physically associated with a therapeutically active component and (b) in contact with the radiopaque marker. The brachytherapy seed has a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge).
Claims60
A brachytherapy seed for implantation into a subject comprising a biocompatible component, a therapeutically active component comprising a non-radioactive drug, and a radiopaque marker, said biocompatible component being (a) physically associated with a therapeutically active component and (b) in contact with said radiopaque marker, wherein said brachytherapy seed has a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge).
A brachytherapy seed for implantation into a subject comprising a non-metal biocompatible component, a therapeutically active component comprising a radioisotope, and a radiopaque marker, said biocompatible component being (a) physically associated with a therapeutically active component and (b) in contact with said radiopaque marker, wherein said brachytherapy seed has a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge).
A method of making a brachytherapy seed for implantation into a subject comprising the steps of:
- (a) providing a biocompatible component, a therapeutically active component comprising a non-radioactive drug, and a radiopaque marker;
- (b) physically associating the biocompatible component, the therapeutically active component, and the radiopaque marker to form a combination product;
- and
- (c) forming the combination product into a seed having a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge).
A method of making a brachytherapy seed for implantation into a subject comprising the steps of:
- (a) providing a biocompatible component, a therapeutically active component comprising a non-radioactive drug, and a sealed container housing a radioisotope;
- a radiopaque marker and
- (b) physically associating the biocompatible component, the therapeutically active component, the container, and the radiopaque marker into a seed such wherein the biocompatible component and the therapeutically active component at least partially coat the container and the seed has a size and shape suitable for passing through the bore of a needle having an interior diameter of less than about 2.7 millimeters (10 gauge).
Dependencies are inferred from the claim text.