Vaccines
AssigneeSmithKline Beecham Biologicals s.a.
InventorsNATHALIE GARCON, PATRICIA MARIE CHRISTINE ALINE FRANCOISE MOMIN
Life of this patent
Estimating the term…
Abstract
The present invention relates to an oil in water emulsion compositions, their use in medicine, in particular to their use in augmenting immune responses to a wide range of antigens, and to methods of their manufacture; the oil in water emulsion comprising a metabolisable oil, a saponin and a sterol.
Claims26
A composition comprising an oil in water emulsion and a saponin, wherein the oil droplets of said oil in water emulsion comprises a metabolisable oil and a sterol.
A method of stabilising a saponin present in the aqueous phase of an oil in water emulsion, comprising the addition of a sterol into the oil phase of said oil in water emulsion.
A method of quenching the reactogenicity of an oil in water emulsion composition, which composition comprises a saponin, said method comprising the addition of a sterol into the oil droplets of said oil in water emulsion.
Dependencies are inferred from the claim text.