Neospora vaccine
AssigneePfizer Inc.
InventorsDavid A. Brake, Manuel Campos
Life of this patent
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Abstract
The present invention provides an homogenate prepared from cells of Neospora, and vaccines against neosporosis prepared therefrom which are useful in the prevention of clinical disease and abortion in mammals.
Claims51
An homogenate prepared from cells of Neospora which is capable of inducing a protective response against neosporosis in a mammal.
A vaccine to protect a mammal against neosporosis, comprising an immunologically effective amount of an homogenate prepared from cells of Neospora, which homogenate is capable of inducing a protective response against neosporosis in a mammal, and a veterinarily acceptable carrier.
A method for preparing a vaccine that protects a mammal against neosporosis, comprising homogenizing cells from Neospora to produce an homogenate capable of inducing a protective response against neosporosis in a mammal, and combining an immunologically effective amount of the homogenate with a veterinarily acceptable carrier.
A method for protecting a mammal against neosporosis, comprising administering to the mammal a vaccine comprising an immunologically effective amount of an homogenate prepared from cells of Neospora, which homogenate is capable of inducing a protective response against neosporosis in a mammal, and a veterinarily acceptable carrier.
A combination vaccine for protecting a mammal against neosporosis and, optionally, one or more other diseases or pathological conditions that can afflict the mammal, which combination vaccine comprises an immunologically effective amount of a first composition comprising an homogenate prepared from cells of Neospora, which homogenate is capable of inducing a protective response against neosporosis in a mammal;
- an immunologically effective amount of a second composition capable of inducing a protective response against a disease or pathological condition that can afflict the mammal;
- and a veterinarily acceptable carrier.
A kit for vaccinating a mammal against neosporosis, comprising a first container having an immunologically effective amount of an homogenate prepared from cells of Neospora, which homogenate is capable of inducing a protective response against neosporosis in a mammal, and a second container having a veterinarily acceptable carrier or diluent.
An antibody specific to an antigenic component present in an homogenate of Neospora cells.
Dependencies are inferred from the claim text.