Prevention and treatment of streptococcal and staphylococcal infection

A method for treating a subject to reduce the likelihood of streptococcal infection comprising

• administering orally to a subject in need of such treatment an agent that binds to a hyaluronic acid-binding region of a CD44 protein in an amount effective to displace streptococcal bacteria bound to CD44 protein in the subject and inhibit streptococcal colonization of the pharynx.

A method for treating a subject to reduce the likelihood of streptococcal infection comprising

• administering orally to a subject in need of such treatment an agent that binds to a hyaluronic acid-binding region of a CD44 protein of a mucosal membrane in an amount effective to interfere with adhesion of streptococcal or staphylococcal bacteria to the mucosal membrane in the subject.

A method for treating a subject to reduce the likelihood of streptococcal or staphylococcal infection comprising administering orally to a subject in need of such treatment an agent that binds to a hyaluronic acid-binding region of a CD44 protein of a mucosal membrane in an amount effective to displace streptococcal or staphylococcal bacteria bound to the mucosal membrane in the subject.

A method for treating a subject to reduce the likelihood of streptococcal or staphylococcal infection comprising

• administering nasally to a subject in need of such treatment who does not have a nasal cavity wound, an agent that binds to a hyaluronic acid-binding region of a CD44 protein of a mucosal membrane in an amount effective to interfere with adhesion of streptococcal or staphylococcal bacteria to the mucosal membrane in the subject.

A method for treating a subject to reduce the likelihood of streptococcal or staphylococcal infection comprising

• administering nasally to a subject in need of such treatment who does not have a nasal cavity wound, an agent that binds to a hyaluronic acid-binding region of a CD44 protein of a mucosal membrane in an amount effective to displace streptococcal or staphylococcal bacteria bound to the mucosal membrane in the subject.

A medicinal product comprising a syrup containing an amount of hyaluronic acid effective to interfere with adhesion of streptococcal bacteria to CD44 protein in a subject and to inhibit streptococcal colonization of a pharynx of the subject.

A medicinal product comprising a syrup containing an amount of hyaluronic acid effective to displace streptococcal bacteria bound to CD44 protein in a subject and to inhibit streptococcal colonization of a pharynx of the subject.

A medicinal product comprising a syrup containing an amount of hyaluronic acid effective to interfere with adhesion of streptococcal or staphylococcal bacteria to a mucosal membrane in a subject.

A medicinal product comprising a syrup containing an amount of hyaluronic acid effective to displace streptococcal or staphylococcal bacteria bound to a mucosal membrane in a subject.

A medicinal product comprising a frozen solution containing an amount of hyaluronic acid effective to interfere with adhesion of streptococcal bacteria to CD44 protein in a subject and to inhibit streptococcal colonization of a pharynx of the subject.

A medicinal product comprising a frozen solution containing an amount of hyaluronic acid effective to displace streptococcal bacteria bound to CD44 protein in a subject and to inhibit streptococcal colonization of a pharynx in the subject.

A medicinal product comprising a frozen solution containing an amount of hyaluronic acid effective to interfere with adhesion of streptococcal or staphylococcal bacteria to a mucosal membrane in a subject.

A medicinal product comprising a frozen solution containing an amount of hyaluronic acid effective to displace streptococcal or staphylococcal bacteria bound to a mucosal membrane in a subject.

A medicinal product comprising a solid solution containing an amount of hyaluronic acid effective to interfere with adhesion of streptococcal bacteria to CD44 protein in a subject and to inhibit streptococcal colonization of a pharynx of the subject.

A medicinal product comprising a solid solution containing an amount of hyaluronic acid effective to displace streptococcal bacteria bound to CD44 protein in a subject and to inhibit streptococcal colonization of a pharynx of the subject.

A medicinal product comprising a solid solution containing an amount of hyaluronic acid effective to interfere with adhesion of streptococcal or staphylococcal bacteria to a mucosal membrane in a subject.

A medicinal product comprising a solid solution containing an amount of hyaluronic acid effective to displace streptococcal or staphylococcal bacteria bound to a mucosal membrane in the subject.