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US 2002/0054903 A1Published application
Direct compression polymer tablet core
OwnerJoseph Tyler, John S. Peterseninventors
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OwnerJoseph Tyler, John S. Peterseninventors
Estimating the term…
The present invention provides a tablet comprising a compressed tablet core which comprises at least about 80% by weight of an aliphatic amine polymer. The invention also provides a method of producing a tablet core comprising at least about 80% by weight of an aliphatic amine polymer resin. The method comprises the step of compressing the aliphatic amine polymer to form the tablet core. The tablet core can further include one or more excipients. In this embodiment, the method of producing the tablet core comprises the steps of: (1) hydrating the aliphatic amine polymer to the desired moisture level; (2) blending the aliphatic amine polymer with the excipients in amounts such that the polymer comprises at least about 80% by weight of the resulting blend; and (3) compressing the blend to form the tablet core. The present invention further relates to a coated tablet comprising an aliphatic amine polymer core wherein the coating is a water based coating.
A tablet comprising a compressed tablet core comprising at least about 80% of a hydrated alkylated amine polymer or a pharmaceutically acceptable salt thereof.
A tablet comprising a compressed tablet core comprising at least about 80% of a hydrated cross-linked alkylated poly(allylamine) or a pharmaceutically acceptable salt thereof.
A tablet comprising a compressed tablet core comprising at least about 80% by weight of hydrated cross-linked alkylated poly(allylamine) hydrochloride.
A compressed tablet comprising an effective disintegrating amount of polyallylamine or a salt thereof with a pharmaceutically acceptable acid.
Dependencies are inferred from the claim text.