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US 2002/0054881 A1Published application
Variants of allergenic proteins of the group 2 of dermatophagoides
AssigneeConsiglio Nazionale Delle Ricerche
InventorsMonica Sturaro, Angelo Viotti, Paolo Falagiani, Giovanni Mistrello, Daniela Roncarolo, Stefania Zanotta
Life of this patent
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Abstract
Variants of allergens of Dermatophagoides pteronyssinus species with reduced allergenic activity.
Claims12
A variant of the natural form of Der p 2, or of an homologous form with sequence identity higher than 85% compared with Der p 2, in which at least one of the Lys residues present at the positions 33, 44, 82, 96, 100, 126 of Der p 2 is substituted and/or deleted.
Dependencies are inferred from the claim text.