Mammalian cytokine; related reagents
OwnerAndrea Knappe, Helmut Fickenscher +1inventors
InventorsANDREA KNAPPE, HELMUT FICKENSCHER, BERNHARD FLECKENSTEIN
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Abstract
Purified genes encoding cytokine from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using said reagents and diagnostic kits are also provided.
Claims20
A substantially pure or recombinant IL-XX protein.
A recombinant nucleic acid comprising sequence at least about 70% identity over a stretch of at least about 30 nucleotides to an IL-XX nucleic acid sequence of SEQ ID NO:
- 1.
A nucleic acid of claim 19, further encoding a polypeptide comprising at least about 60% identity over a stretch of at least about 20 amino acids to an IL-XX sequence of SEQ ID NO:
- 2.
A method of treating a patient having an abnormal immune response by administering to said patient an effective dose of:
- a) an antibody or binding partner which binds specifically to an IL-XX;
- b) a substantially pure IL-XX protein or peptide thereof;
- or
- c) a nucleic acid encoding an IL-XX peptide.
Dependencies are inferred from the claim text.