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US 2002/0025938 A1Published application
Macrolide intermediates in the preparation of clarithromycin
AssigneeBiochemie
InventorsVictor Centellas, Jose Diago
Life of this patent
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Abstract
The present invention relates to a process for the production of clarithromycin from an aqueous medium in anhydrous form and in the form of a hydrate.
Claims12
A process for the production of a compound of formula I,
- 2
- which comprises the steps of:
- (i) producing a solution of a compound of formula I in the form of a salt in a solvent,
- (ii) adjusting the pH, and
- (iii) isolating a compound of formula I,
- characterised in that the solvent in step (i) is an aqueous solvent medium which is selected from water or a mixture of water and organic solvent.
3 more elements
Dependencies are inferred from the claim text.