Production of polyketides in plants
OwnerMary C. Betlach, James T. Kealey +2inventors
InventorsMary C. Betlach, James T. Kealey, Neal Gutterson, Ed Ralston
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Abstract
The present invention provides genetically altered plants and plant cells that have been modified to contain expression system(s) capable of expressing a functional polyketide synthase (PKS). The present invention further provides methods of producing PKS and polyketides using these plants and cells.
Claims33
Plant cells, plant parts or plants modified to contain at least one expression system effective to produce at least a minimal aromatic polyketide synthase (PKS), wherein said minimal aromatic PKS comprises a ketosynthase/acyl transferase (KS/AT) catalytic region, a chain-length factor (CLF) catalytic region and an acyl carrier protein (ACP) activity.
A plant cell, plant part or plant modified to contain at least one expression system effective to produce at least a minimal modular polyketide synthase (PKS), wherein said minimal PKS comprises a KS catalytic region, an AT catalytic region, and an ACP activity.
Plant cells, plant parts or plants modified to contain at least one expression system effective to produce at least a minimal fungal polyketide synthase (PKS) wherein said minimal PKS comprises a ketosynthase/acyl transferase (KS/AT) catalytica region, and an acyl carrier protein (ACP) activity.
Dependencies are inferred from the claim text.