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US 2002/0002202 A1Published application
Use of fumarate salt of L-carnitine or its alkanoyl derivatives in ischaemia
OwnerClaudio Cavazza, Arduino Arduiniinventors
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Abstract
The invention described herein relates to the use of L-carnitine or one of its alkanoyl derivatives with formula (I) where R is an alkanoyl group with from 2 to 8 carbon atoms, and X− is the acid fumarate anion, for the preparation of a medicine useful in the treatment and prevention of organ ischemia.
Claims14
Use of L-carnitine or alkanoyl L-carnitine acid fumarate or of one of its alkanoyl derivatives with formula
- 2
- where R is hydrogen or an alkanoyl group with from 2 to 8 carbon atoms and X− is the acid fumarate anion, for the preparation of a composition suitable for reducing the risk of onset of organ ischemia, and for preventing and/or therapeutically treating it, particularly as affecting the cardiocirculatory apparatus, with the proviso that said composition does not contain antioxidants.
Use according to any of claims 1-4, in which R is hydrogen.
Container containing:
- a) L-carnitine acid fumarate;
- or
- a composition containing L-carnitine acid fumarate or alkanoyl L-carnitine acid fumarate as active ingredient, or L-carnitine or alkanoyl L-carnitine inner salt or one of its pharmacologically acceptable salts and fumaric acid in a mixture with one another or packaged separately, in substantially equimolar amounts, the container bearing an indication that the L-carnitine acid fumarate or the composition containing it or the mixture of L-carnitine and fumaric acid or these ingredients packaged separately are suitable for reducing the risk of the onset of organ ischemia, and for preventing and/or therapeutically treating it, particularly as affecting the cardiocirculatory apparatus.
Dependencies are inferred from the claim text.