Method and composition for treatment of inflammatory conditions
OwnerPol-Henri Guivarc'h, Gary Robinsoninventors
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Abstract
Methods of treating inflammation of the gastrointestinal tract and/or systemic or local inflammation by administering a steroid anti-inflammatory or a non-steroid anti-inflammatory drug in conjunction with polyunsaturated fatty acids or their derivatives and optionally also a pharmacologically active antioxidant and compositions for practicing these methods are described.
Claims37
A method of treating inflammation of the gastrointestinal tract and/or systemic or local inflammation in an animal comprising administering to an animal in need of same an effective amount of an anti-inflammatory drug and omega-3 and/or omega-6 and/or omega-9 polyunsaturated fatty acids, or their derivatives.
A pharmaceutical composition for the treatment of inflammatory conditions in mammals, said composition consisting essentially of budesonide, or its prodrugs or derivatives, and a lipid source of omega-3 and/or omega-6 and/or omega-9 polyunsaturated fatty acids, or their derivatives, optionally also including pharmaceutically acceptable carriers, including other essential and non-essential oils, diluents, viscosity-modifiers, stabilizers, erodable or swallowable matrices, and penetration enhancers.
An orally or enterally administrable composition for the treatment of inflammatory conditions of the gastrointestinal tract consisting essentially of effective amounts of budesonide, or its prodrugs or derivatives, a highly purified oil source of omega-3 and/or omega-6 and/or omega-9 polyunsaturated fatty acids, and antioxidants, optionally together with pharmaceutically acceptable carriers, diluents, viscosity-modifiers, stabilizers, and erodable or swallowable matrices.
An orally administrable composition for the treatment of systemic or local inflammatory conditions consisting essentially of effective amounts of budesonide, or its prodrugs or derivatives, a highly purified oil source of omega-3 and/or omega-6 and/or omega-9 polyunsaturated fatty acids, and antioxidants, optionally including pharmaceutically acceptable carriers, diluents, viscosity-modifiers, stabilizers, erodable or swallowable matrices, and penetration enhancers.
A topically administrable composition for the treatment of systemic or local inflammatory conditions consisting essentially of effective amounts of budesonide, or its prodrugs or derivatives, omega-3 and/or omega-6 and/or omega-9 polyunsaturated fatty acids and antioxidants, optionally including pharmaceutically acceptable carriers, diluents, viscosity-modifiers, stabilizers, erodable matrices, and penetration enhancers.
A pharmaceutical composition for the treatment of inflammatory conditions in mammals, said composition consisting essentially of a steroid or non-steroidal anti-inflammatory drug and omega-3 and/or omega-6 and/or omega-9 polyunsaturated acid or their derivatives, optionally also including pharmaceutically acceptable carriers, diluents, viscosity-modifiers, stabilizers, erodable and swallowable matrices, and penetration enhancers.
Dependencies are inferred from the claim text.