Pharmaceutical preparations for treating side effects during and/or after gnrha therapy
OwnerMichael Oettel, Ludwig Wildt +4inventors
InventorsMICHAEL OETTEL, LUDWIG WILDT, PETER LICHT, JOACHIM NEUWINGER, WOLFGANG HUMMEL, RALPH DITTRICH
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Abstract
The pharmaceutical preparations for treating side effects, such as hot flashes, during and/or after treatment with analogs or antagonists of gonadotropin releasing hormone (GnRHa therapy) contain an effective amount of 17α-estradiol, its chemically modified derivatives, chemically modified derivatives of 17β-estradiol or estriol.
Claims4
A pharmaceutical preparation for treating side effects during and/or after treatment with analogs or antagonists of gonadotropin releasing hormone, said pharmaceutical preparation containing an effective amount of at least one active ingredient selected from the group comprising 17α-estradiol, chemically modified derivatives of said 17α-estradiol, chemically modified derivatives of 17β-estradiol and chemically modified derivatives of estriol.
A pharmaceutical preparation for treating side effects during and/or after treatment with analogs or antagonists of gonadotropin releasing hormone, said pharmaceutical preparation containing an effective amount of at least one active ingredient selected from the group consisting of 17α-estradiol, ent-17α-estradiol, 4-methyl-estra-1,3,5(10)-triene-1,17α-diol, 4-methylestra-1,3,5(10),6-tetraene-1,17α-diol, 4-methylestra-1,3,5(10),6,8-pentaene-1,17β-diol, ent-estradiol, 4-methylestra-1,3,5(10),6-tetraene-1,17α-diol, 4-methylestra-1,3,5(10),6,8-pentaene-1,17β-diol, 17α-4′-hydroxyphenylmethyl-4-methylestra-1,3,5(10)-triene-1,17β-diol, 17α-4′-hydroxyphenoxymethyl-4-methylestra-1,3,5(10)-triene-1,17β-diol, 17α-4′-hydroxy-thiophenoxymethyl-4-methylestra-1,3,5(10)-triene-1,17β-diol, 17α-4′-dimethylaminophenylmethyl-4-methylestra-1,3,5(10)-triene-1,17β-diol, 17α-3′,5′-dimethyl-4-hydroxyphenylmethyl-4-methylestra-1,3,5(10)-triene-1,17β-diol, 17α-3′,5′-dimethyl-4′-hydroxyphenylmethyl-4-methylestra-1,3,5(10),6-tetraene-1,17β-diol, 17α-4′-hydroxyphenoxylmethyl-4-methylestra-1,3,5(10),6-tetraene-1,17β-diol, 14β,15β-methylene-8-dehydroestradiol, 6-dehydroestriol and 9(11)-dehydroestriol.
Dependencies are inferred from the claim text.