Genomic analysis of tRNA gene sets
OwnerWayne Mitchell, T. Guy Robertsinventors
Life of this patent
Estimating the term…
Abstract
Methods for identifying one or more positions of conserved difference in a set of similar sequence strings are provided, as well as systems and devices for identifying one or more positions of conserved difference in a set of similar sequence strings, and sets of positions of conserved differences.
Claims28
A method for identifying one or more positions of conserved difference in a set of similar sequence strings, the method comprising:
- providing a set of similar sequence strings derived from a plurality of species, wherein each similar sequence string comprises at least n sequence elements;
- comparing the at least n sequence elements in a first similar sequence string to the at least n sequence elements in a second similar sequence string, for a first species of the plurality of species;
- assigning a value to each of n positions of the at least n sequence elements, based upon whether the sequence elements are identical or different in the two similar sequence strings;
- repeating the comparing and assigning for each species in the plurality of species;
- summing the values assigned for each of the n positions across the plurality of species;
- and
- identifying which of the n positions have the greatest sum value, thereby identifying the positions of conserved difference in the set of similar sequence strings.
A method for identifying one or more positions of conserved difference in a set of similar sequence strings, the method comprising:
- providing a set of similar sequence strings derived from a plurality of species, wherein each similar sequence string comprises at least n sequence elements, and wherein each species in the plurality of species contributes two or more similar sequence strings to the set of similar sequence strings;
- simultaneously comparing the at least n sequence elements for the two or more similar sequence strings from a first species of the plurality of species;
- assigning a value to each of n positions of the at least n sequence elements, based upon whether the sequence elements are identical or different in the two or more similar sequence strings;
- repeating the comparing and assigning for each species in the plurality of species;
- summing the values assigned for each of the n positions across the plurality of species;
- and
- identifying which of the n positions have the greatest sum value, thereby identifying the positions of conserved difference in the set of similar sequence strings.
A computer or computer-readable medium comprising one or more logical instructions for identifying at least one conserved difference in a set of similar sequence strings derived from a plurality of species,
- wherein each species in the plurality of species comprises at least two similar sequence strings;
- and
- wherein the logical instructions compare at least n sequence elements in a first similar sequence string to at least n sequence elements in a second similar sequence string, for a first species of the plurality of species;
- assigns a value to each of n positions of the at least n sequence elements, based upon whether the sequence elements are identical or different in the two similar sequence strings;
- repeats the comparing and assigning for each species in the plurality of species;
- sums the values assigned for each of the n positions across the plurality of species;
- and identifies which of the n positions have the greatest sum value, thereby identifying the positions of conserved difference in the set of similar sequence strings.
Dependencies are inferred from the claim text.