Apparatus and method for coating a material
AssigneeScientec Research Pty. Ltd
InventorsMICHAEL FRANCIS O'DONOGHUE, JAMES ALLAN MORRIS
Life of this patent
Estimating the term…
Abstract
The invention generally provides a method of coating a material, the method including the following steps: (a) forming a generally elongate coating structure (15), the coating structure having an internal cavity (17) extending at least substantially along its length, and wherein the internal cavity of the coating structure is capable of receiving a core material (21); (b) inserting a core material (21) into the internal cavity (17) of the coating structure (15); (c) compressing the coating structure at a first location (44) along its length so as generally to form a seal at that location; and (d) compressing the coating structure at a second location along its length (45).
Claims31
A method of producing a delivery device for the controlled release of a bioactive substance, comprising the following steps:
- (a) forming a generally elongate coating structure to coat a core material containing the bioactive substance, the coating structure having an internal cavity extending at least substantially along its length, and wherein the internal cavity of the coating structure is capable of receiving a core material:
- (b) inserting the core material into the internal cavity of the coating structure;
- (c) compressing the coating structure at a first location along its length so as generally to form a seal at that location;
- and
- (d) compressing the coating structure at a second location along its length.
A method as claimed in any of the preceding claims, in which the coating structure is formed as a single layer.
A method as claimed in any of the preceding claims, in which the core structure comprises:
- (a) a tablet;
- (b) a gel;
- (c) a paste;
- (d) granules;
- (e) powder;
- (f) a fluid;
- or
- combinations of two or more of (a) to (e).
A method as claimed in any of the preceding claims, in which the core material comprises:
- (a) a bioactive substance selected from the group consisting of:
- (i) natural, synthetic or recombinant pharmacological agents;
- (ii) food additives;
- (iii) food supplements;
- (iv) antigens;
- (v) antibodies;
- (vi) cytokines;
- (vii) growth promotants;
- (viii) hormones;
- (ix) vaccines;
- (x) cancer cell inhibitory agents;
- (xi) immuno-suppressants;
- (xii) immuno-stimulants;
- (xiii) antimicrobial agents;
- (xiv) anti-viral agents;
- (xv) vitamins;
- (xvi) minerals;
- (xvii) organic nutrients;
- (xviii) inorganic nutrients;
- or
- combinations of two or more of the aforegoing;
- and
- (b) optionally, pharmaceutically or veterinarily acceptable carriers and/or excipients.
A method as claimed in any of the preceding claims, in which the step of compressing the coating structure at the first location along its length so as generally to form a seal at that location comprises the step of bringing two or more mutually opposed surfaces of the coating structure into contact with one another, so as generally to form a seal at that location.
A method as claimed in any of the preceding claims, in which the step of compressing the coating structure at the second location along its length comprises the step of bringing two or more mutually opposed surfaces of the coating structure together, so as to form a seal at that location.
An apparatus for producing a controlled release delivery device for a bioactive substance, comprising:
- (a) means for forming a generally elongate coating structure to coat a core material containing a bioactive substance, and wherein the coating structure has an internal cavity extending at least substantially along its length capable of receiving the core material therein;
- (b) means for inserting the core material into the internal cavity of the coating structure;
- (c) means for compressing the coating structure at a first location along its length;
- and
- (d) means for compressing the coating structure at a second location along its length.
Dependencies are inferred from the claim text.