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OwnerMichael J. Oldham, Howard C. Krivan +1inventors
InventorsMICHAEL J. OLDHAM, HOWARD C. KRIVAN, RICHARD C. POTTER
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Diseases and disorders of dermal tissue such as the skin, hair and nails are treated or prevented by administering one or more lectins, capable of binding to the surface of pathogenic microorganisms inhabiting the hair, skin, and nails, or of binding to the superficial tissues that comprise hair, skin, and nails. The lectins may be administered topically or subcutaneously to a patient infected with pathogenic microorganisms or in danger of being exposed to such pathogens. Lectins that stimulate cell mitosis may also be administered to accelerate wound healing and restore the appearance of age-wrinkled skin. Lectins that coagulate blood can be administered to assist in stopping bleeding from skin lesions. The lectins may be applied to the skin in a pharmceutically acceptable vehicle.
A method of preventing and/or treating diseases and disorders of dermal tissue such as the skin, hair, or nails of humans and other animals caused by pathogenic microorganisms which comprises locally administering to a cutaneous site at least one lectin capable of interfering with the infective capability of a pathogenic microorganism toward dermal tissue, in an amount effective to diminish said infective capability of said microorganism.
A method of alleviating age-induced skin wrinkles in humans comprising locally administering to skin tissue afflicted with wrinkles at least one lectin capable of inducing cell mitosis in the tissues comprising the wrinkled area in an amount effective to decrease the prominence of said wrinkles.
A method of promoting the healing of dermal wounds and burns in humans and other animals comprising locally administering to injured skin tissue at least one lectin capable of inducing cell mitosis in said injured tissue in an amount effective to promote healing of said injured tissues.
A method of promoting the coagulation of blood from skin lacerations or open surgical incisions in humans and other animals comprising locally administering to a bleeding lesion at least one lectin capable of agglutinating blood or blood constituents in an amount effective to promote healing of said injured tissues
A method of preventing syphilis in human males which comprises locally administering to the penis of a human male at least one lectin capable of binding to Treponema pallidum or to superficial receptor sites for Treponema pallidum on penile tissues, said lectin being effective for diminishing the infective capability of Treponema pallidum, and said lectin being administered in an amount effective to diminish said infective capability of T. pallidum.
A pharmaceutical composition for administering lectins to the skin comprising at least one lectin dispersed in a pharmaceutically acceptable vehicle.
Dependencies are inferred from the claim text.