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US 2002/0001593 A1Published application
Hemolysin fusion proteins, their production and use
OwnerPeter O'Hanley, Guy LaLondeinventors
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Abstract
Novel hemolysin fusion proteins can be produced by inserting a foreign nucleotide sequence encoding an immunogenic peptide in a region of HlyA corresponding to the CnBr II through CnBr V region of HlyA.
Claims7
An immunogenic hemolysin fusion protein comprising at least one foreign amino acid sequence inserted into a deleted region of HlyA, wherein said deleted region reduces or eliminates hemolysin-mediated pore formation.
Dependencies are inferred from the claim text.