System and method for generating a profile of particulate components of a body fluid sample
AssigneeTel Aviv Medical Center Research Development Fund
InventorShlomo Berliner
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Abstract
A system for generating a profile of particulate components of a body fluid sample is provided. The system includes: (a) a device for causing controlled flow of the body fluid sample on a substrate, the controlled flow of the body fluid sample leading to a differential distribution of the particulate components on the substrate; and (b) a magnifying device being for providing a magnified image of differentially distributed particulate components on the substrate, the magnified image representing a profile of the particulate components of the body fluid sample.
Claims64
A system for generating a profile of particulate components of a body fluid sample comprising:
- (a) a device for causing controlled flow of the body fluid sample on a substrate, said controlled flow of the body fluid sample leading to a differential distribution of the particulate components on said substrate;
- and
- (b) a magnifying device being for providing a magnified image of differentially distributed particulate components on said substrate, said magnified image representing a profile of said particulate components of the body fluid sample.
A system for generating a profile of particulate components of a body fluid sample comprising:
- (a) at least one apparatus for generating a profile of the particulate components of the body fluid sample, said at least one apparatus including:
- (i) a device for causing controlled flow of the body fluid sample on a substrate, said controlled flow of the body fluid sample leading to a differential distribution of the particulate components on said substrate;
- and
- (ii) a magnifying device being for providing a magnified image of differentially distributed particulate components on said substrate, said magnified image representing a profile of said particulate components of the body fluid sample, and
- (iii) an imaging device being for capturing said magnified image provided by said magnifying device;
- (b) an image analyzer being in communication with said at least one apparatus, said image analyzer being configured for analyzing the profile of said particulate components in the body fluid sample;
- and
- (c) at least one communication server being for communicating said magnified image from said at least one apparatus to said image analyzer.
A method of generating a profile of particulate components in a body fluid sample comprising the steps of:
- (a) causing controlled flow of the body fluid sample on a substrate, said controlled flow of the body fluid sample leading to a differential distribution of the particulate components on said substrate;
- and
- (b) providing a magnified image of differentially distributed particulate components on said substrate, said magnified image representing a profile of said particulate components in the body fluid sample.
A method of determining an atherosclerosis risk factor of an individual, the method comprising the steps of:
- (a) causing controlled flow of a body fluid sample obtained from the individual on a substrate, said controlled flow of said body fluid sample leading to a differential distribution of particulate components included in said body fluid sample on said substrate;
- (b) providing a magnified image of differentially distributed particulate components on said substrate, said magnified image representing a profile of said particulate components in the body fluid sample;
- (c) analyzing at least one parameter of said profile to thereby determine the atherosclerosis risk factor of the individual.
A method of generating a profile of a body fluid sample comprising the steps of:
- (a) causing controlled flow of the body fluid sample on a substrate, said controlled flow of the body fluid sample leading to a distribution of the body fluid sample on said substrate;
- and
- (b) determining a thickness variance of the body fluid sample along a direction of said controlled flow on said substrate, said thickness variance representing a profile of the body fluid sample.
A carrier comprising a plurality of lanes each occupying a length, and a portion of a width, of a surface of the carrier, each lane of said plurality of lanes being coated with a specific molecule capable of binding a specific cell type present in a biological sample.
Dependencies are inferred from the claim text.