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US 2001/0056231 A1Published application
High resolution MRI imaging of brain functions
OwnerAndrzej Jesmanowicz, James S. Hyde +1inventors
InventorsAndrzej Jesmanowicz, James S. Hyde, Bharat B. Biswal
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Abstract
An EPI pulse sequence is performed by an NMR system which acquires images of the brain over a time interval during which the subject performs a function or is stimulated in a pattern. The voxel size of acquired images corresponds to the anatomy of cortical microcirculation structures which range from 1 to 2 mm along all three axes. A centric view order is employed and one-half of k-space is sampled to reduce scan time for each image.
Claims10
A method for producing a functional magnetic resonance image (fMRI) of a subject's brain, the steps comprising:
- a) operating a magnetic resonance imaging (MRI) system to perform a series of pulse sequences that acquire a series of NMR k-space data arrays over a period of time, during which the subject's brain is caused to function in a preselected temporal pattern;
- b) producing a time course NMR image data set of time domain voxel vectors from the series of k-space arrays, in which each time domain voxel vector indicates the NMR signal during said period of time from a substantially cubic region of the brain having a size from 1.0 to 8.0 mm3;
- c) producing an image which indicates the amount of brain activity in each of said cubic regions.
Dependencies are inferred from the claim text.