Agents, and methods employing them, for the prevention or reduction of tissue adhesion at a wound site
AssigneeMedicarb AB
InventorsHANS-ARNE HANSSON, GUNILLA JOHANSSON-RUDEN, OLLE LARM
Life of this patent
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Abstract
The use of chitosan and a polysaccharide immobilized thereto selected from heparin, heparan sulphate and dextran sulphate for the manufacture of an agent capable of preventing or substantially reducing undesirable adhesion of damaged tissue with adjacent or surrounding tissues in connection with wound healing; and a process for the use of such agent.
Claims14
The use of chitosan and a polysaccharide immobilized thereto selected from heparin, heparan sulphate and dextran sulphate for the manufacture of an agent capable of preventing or substantially reducing undesirable adhesion of damaged tissue with adjacent or surrounding tissues in connection with wound healing.
The use according to any one of the preceding claims, characterized in that the polysaccharide is heparin or heparan sulphate.
The use according to any one of the preceding claims, characterized in that the agent is in the form of a film or membrane.
The use according to any one of the preceding claims, characterized in that the chitosan has a degree of N-acetylation of at most about 90% and preferably at most about 50%.
A process to prevent or substantially reduce undesireable adhesion of tissues in connection with wound healing, characterized by applying at the site of the wound healing an agent comprising chitosan and a polysaccharide immobilized thereto selected from heparin, heparan sulphate and dextran sulphate.
Dependencies are inferred from the claim text.