Back to results
US 2001/0055797 A1Published application
Sol-gel biomaterial immobilization
OwnerJohn F.T. Conroy, Pamela M. Norris +1inventors
InventorsJohn F.T. Conroy, Pamela M. Norris, Mary E. Power
Life of this patent
Estimating the term…
Abstract
A sol and a method for forming a sol that can be used to immobilize biological materials and/or form robust macroporous gels. As needed, sols that are compatible with biological materials can be produced. Also as needed, robust macroporous gels can be formed by introducing dispersants to suitable sols.
Claims25
A method, comprising:
- hydrolyzing a sol-gel precursor in water to form a sol containing an organic solvent;
- removing said organic solvent from said hydrolyzed sol;
- and
- mixing said biological material with said hydrolyzed sol after said removing step.
1 more element
A method comprising:
- providing a sol solution having less than 29 mole % organic solvents to make said sol compatible with a biological material;
- and
- immobilizing said biological material by mixing said biological material into said sol.
A method comprising:
- hydrolyzing a sol-gel precursor in water to form a sol containing an organic solvent;
- mixing said biological material with said sol;
- mixing a sufficient amount of a dispersant into said sol to cause macropores in a gel formed by said sol.
A sol, comprising:
- a species formed by the hydrolysis of P moles of a sol-gel precursor;
- a sol solution including 71 mole % or more water and 29 mole % or less organic solvents;
- and
- a biological material, wherein said sol solution is compatible with said biological material.
1 more element
A sol, comprising:
- a species formed by the hydrolysis of P moles of a sol-gel precursor;
- W moles of water;
- a sufficient amount of a dispersant to cause macropores in a gel formed by said sol;
- and
- a biological material.
2 more elements
Dependencies are inferred from the claim text.