Method and device for preparing a dental implant by immersion in a culture of mesenchymal cells

A method of manufacturing a dental implant comprising:

• preparing an implant composed of a root portion and a crown portion and constituted by an inert biocompatible material in a shape which is adapted to an extracted tooth;
• immersing the root portion of said implant in a culture of undifferentiated mesenchymal cells with an apparatus comprising a culture dish (10) the shape of which comprises a longitudinal axis, said culture dish being closed by a cover (11) and containing a porous wall (20) delimiting a first space (21) containing the cell culture medium, and a second space (22) containing the cells being cultured, and in which the root portion of the implant is immersed, said wall having a configuration such that a gap 0.1 to 5 mm is left between the root portion of the implant and the wall, creating an artificial alveolus,
• the culture of mesenchymal undifferentiated cells as above-mentioned and in a culture medium the composition of which allows differentiation into cementoblasts and fibroblasts, over a period which is sufficient for said differentiation and for adhesion of cementoblasts to the root portion and the formation of a first layer of cementum and of an alveolodental ligament primordium attached to said cementum;
• recovering the implant carrying differentiated tissues affixed to its root portion.