Back to results
US 2001/0055607 A1Published application
Compositions, kits, and methods for inhibiting cerebral neurovascular disorders and muscular headaches
OwnerBruce H. Levininventor
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
OwnerBruce H. Levininventor
Estimating the term…
Methods, kits, and compositions for inhibiting a cerebral neurovascular disorder or a muscular headache in a human patient are provided. The methods comprise intranasally administering to the patient a pharmaceutical composition comprising a local anesthetic, and preferably a long-acting local anesthetic ingredient. A composition useful for practicing the methods of the invention is described which comprises at least one local anesthetic in a pharmaceutically acceptable carrier, wherein the composition is formulated for intranasal delivery. Cerebral neurovascular disorders include migraine and cluster headache. Muscular headaches include tension headaches and muscle contraction headaches. A kit comprising the composition and an intranasal applicator and a method of systemically delivering a pharmaceutically active agent to an animal are also included in the invention.
A method of inhibiting a cerebral neurovascular disorder in a human patient, the method comprising intranasally administering to the patient a long-acting local anesthetic pharmaceutical composition in an amount effective to inhibit the cerebral neurovascular disorder.
A method of inhibiting a muscular headache in a human patient, the method comprising intranasally administering to the patient a local anesthetic in an amount effective to inhibit the muscular headache.
A method of inhibiting a cerebral neurovascular disorder in a human patient, the method comprising anesthetizing a nerve structure associated with the disorder in the patient for a period effective to inhibit the disorder.
A method of systemically administering a pharmaceutically active agent to a mammal, the method comprising non-intravenously administering to the mammal a composition comprising a pharmaceutically effective amount of at least one local anesthetic and a pharmaceutically effective amount of the pharmaceutically active agent.
A pharmaceutical composition useful for inhibiting a cerebral neurovascular disorder or a muscular headache in a human patient, the composition being formulated for intranasal delivery and comprising at least one local anesthetic, wherein a single intranasally administered dose of the composition inhibits the cerebral neurovascular disorder or muscular headache.
Dependencies are inferred from the claim text.