US 2001/0044482 A1 · Interpenetrating polymer network hydrophilic hydrogels for contact lens

Abstract

An interpenetrating polymer network (IPN) composition and a process for the manufacture of hydrogel contact lens using the invention material. The polymeric materials are formed by polymerization of: (1) an unsaturated alkyl(meth)acrylate or its derivatives such as 2-hydroxyethyl methacrylate as the principle monomer; (2) optionally vinyl containing comonomer(s) to enhance the resulting hydrogel water absorbing capability; (3) polymerizable multi-functional crosslinking agent(s); (4) an irradiation initiator and/or thermal initiator; (5) optionally other additives to impart the resulting hydrogel specific properties such as ultra-violet blocking ability and handling colors; in the presence of a soluble, hydrophilic IPN agent such as polyvinylpyrrolidone (PVP) or poly-2-ethyl-2-oxazoline (PEOX) with a specific molecular weight range. The novel hydrophilic hydrogel material in the present invention can be used to produce a spherical contact lens, a toric contact lens, a multifocal contact lens, a toric-multifocal contact lens, and other medical devices. The inventive hydrogel material shows a low degree of surface friction, a low dehydration rate, and a high degree of biodeposit resistance.

Claims16

Dependent claims

A hydrogel composition comprising:

I. at least one polymer;
and
II. at least one interpenetrating polymer network agent, interpenetrating said at least one polymer, selected from the group consisting of:
(A) at least one polymer comprising one or more monomeric units comprising at least one ═N—C(═O)— group;
(B) at least one polymer comprising one or more monomeric units comprising at least on N-oxide group;
(C) at least one polymer comprising both ═N—C(═O)— and N-oxide groups of (A) and (B);
and
(D) mixtures thereof;
III. at least one polymer crosslinker selected from the group consisting of polyethylene glycol dimethacrylate and ethylene glycol dimethacrylate;
and
IV. optionally, at least one material selected from the group consisting of monomers, polymerization initiators, ultraviolet absorbing materials, colorants, antiseptic agents, and combinations thereof.

8 more elements

A hydrogel composition comprising:

I. at least one polymer;
and
II. at least one interpenetrating polymer network agent, interpenetrating said at least one polymer, selected from the group consisting of:
(A) at least one polymer comprising one or more monomeric units comprising at least one ═N—C(═O)— group;
(B) at least one polymer comprising one or more monomeric units comprising at least on N-oxide group;
(C) at least one polymer comprising both ═N—C(═O)— and N-oxide groups of (A) and (B);
and
(D) mixtures thereof;
III. at least one sulfoxide containing material selected from the group consisting of sulfoxide-containing methacrylates, sulfoxide containing acrylates, and combinations thereof;
and
IV. optionally, at least one material selected from the group consisting of monomers, polymer crosslinkers, polymerization initiators, ultraviolet absorbing materials, colorants, antiseptic agents, and combinations thereof.

8 more elements

Dependencies are inferred from the claim text.

Interpenetrating polymer network hydrophilic hydrogels for contact lens

Life of this patent

Interpenetrating polymer network hydrophilic hydrogels for contact lens

Life of this patent

Abstract

Claims16