Methods, compositions, and kits for enhancing female sexual desire and responsiveness
AssigneeVivus, Inc.
InventorGary W. Neal
Life of this patent
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Abstract
Topical application of a prostaglandin directly to the clitoris is effective for enhancing female sexual desire and responsiveness.
Claims39
A method for enhancing female sexual desire and response, comprising topically administering to the clitoris of a subject in need thereof an effective amount of a prostaglandin.
A pharmaceutical composition, comprising:
- (a) a prostaglandin;
- and
- (b) a pharmaceutically acceptable carrier;
- wherein said pharmaceutical composition is selected from the group consisting of (a) aqueous compositions having a pH of 3 to 7;
- and (b) nonaqueous compositions which further comprise a pharmaceutically acceptable citrate buffer which when dissolved in sufficient water to be 0.01 Molar in citrate affords an aqueous solution having a pH of 3 to 7.
A kit, comprising:
- (a) means for containing a prostaglandin or a pharmaceutical composition comprising a prostaglandin;
- and
- (b) means for administering a prostaglandin or a pharmaceutical composition comprising a prostaglandin to the clitoris,
- wherein said means for containing contains a prostaglandin or a pharmaceutical composition comprising a prostaglandin.
A method of diagnosing female sexual dysfunction, comprising monitoring the baseline clitoral temperature of the clitoris in a female, administering a prostaglandin agent, known to cause a sexual response when applied to a clitoris, to the clitoris of said female, measuring the clitoral temperature response of said female to said administering, and comparing said clitoral temperature response of said female to that found in females not suffering sexual dysfunction.
A pharmaceutical composition, comprising:
- (a) a prostaglandin;
- (b) a PGDH inhibitor;
- and
- (c) a triglyceride carrier.
Dependencies are inferred from the claim text.