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US 2001/0044158 A1Published application
Diagnostic assay for endometriosis
OwnerGrant R. Yeamaninventor
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Abstract
The present invention provides a method for detecting endometriosis in a patient and is an improvement over invasive and expensive surgical procedures. The method employs immunoassays which detect autoantibodies in a serum sample which react with Thomsen-Friedenreich antigen (Tf). Increased levels of autoantibodies in a serum sample from the patient which bind to Tf-like antigen is indicative of endometriosis in the patient.
Claims12
A method for diagnosing endometriosis in a patient, said method comprising:
- (a) obtaining a serum sample from said patient,
- (b) incubating Thomsen-Friedenreich (Tf)-like antigen with said serum sample,
- (c) detecting autoantibody reactivity with the Tf-like antigen in the sample, and;
- (d) correlating an increased level of autoantibody reactivity to the Tf-like antigen in the serum sample with a diagnosis of endometriosis in said patient.
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Dependencies are inferred from the claim text.