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OwnerHiep Huatan, Alison Jane Soards Nock +1inventors
InventorsHiep Huatan, Alison Jane Soards Nock, Dimitris Papadopoulos
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A formulation suitable for oral treatment with a medicament comprising: a solid masticable portion and one or more reservoir portions encompassed by said masticable portion; the solid masticable portion consisting of a fully edible material, having mechanical properties conducive to promoting mastication, typified by a stiffness measurement (i.e. Young's modulus) in the range of 0.01-5 MPa, and compressive strength in the range of 10 to 10,000 mJ; the reservoir portion or portions comprising a releasable unit dose of the medicament in a fluid (preferably a liquid) form, with a viscosity below 800 mPa.s at body temperature (ca. 36-ca.40° C.), and preferably between the range of 50-200 mPa.s; such that on mastication, the masticable portion is ruptured and the unit dose of the medicament is released in a short space of time from the reservoir portion into the oral cavity.
An oral formulation for a medicament comprising:
A formulation according to any previous claim wherein the reservoir portion is up to 40% by volume of the formulation.
A formulation according to any previous claim wherein the shape of the formulation is substantially hemispherical.
A formulation according to any previous claim wherein the medicament is present at up to about 3% by weight.
A formulation according to any previous claim wherein the medicament is one that reduces plaque, controls gingivitis, prevents calculus, prevents halitosis or prevents periodontitis.
A method of treatment of a human or non-human animal subject in need of treatment with a medicament comprising administration of a formulation of said medicament according to any previous claim.
Dependencies are inferred from the claim text.