Methods and apparatus for using controlled heat to regulate transdermal and controlled release delivery of fentanyl, other analgesics, and other medical substances
AssigneeZars, Inc.
InventorsJie Zhang, Wade Hull, Larry Rigby, Theodore Stanley
Life of this patent
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Abstract
The present invention is directed toward an apparatus to rapidly deliver a drug to a patient The invention comprises a drug beneath a patient's skin in a drug depot site. A heating component is placed near the drug depot site and generates heat in and near the drug depot site. A control component connected to the heating component is used to control the magnitude and duration of heat generated by the heating component.
Claims61
An apparatus to rapidly deliver a drug to a patient comprising:
- a drug in a drug depot site,
- a heating component to generate heat for heating the drug depot site;
- and
- a control component capable of controlling the magnitude and duration of heat generated by the heating component.
The apparatus of claim 3, wherein said storage of said drug creates the “depot site.”
An apparatus to rapidly drug to a patient comprising:
- a drug in a drug depot site,
- a heating component to generate heat for heating the drug depot site wherein the heating component generates heat by chemical reaction, and
- a control component capable of controlling the amount of heat generated by the heating component.
An apparatus for delivering drug to a patient comprising:
- a drug in a drug depot site,
- a heating component comprising a plurality of sub-heating elements to generate heat for heating the drug depot site and
- a control component capable of controlling the amount of heat generated by the heating component.
A method of drug delivery comprising the steps of:
- creating a drug depot site beneath a patient's skin;
- and
- selectively applying controlled heat to at least a portion of the depot site to release a portion of the drug from the depot site to the systemic circulation
A method of drug delivery to a patient comprising the steps of:
- placing the fentanyl patch on the patient's skin as part of a surgery related anesthesia;
- placing the heating patch proximate to the fentanyl patch on the patient's skin;
- selecting settings on a control component that controls heating;
- and
- heating until to release drug from a patients drug depot.
Dependencies are inferred from the claim text.