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US 2001/0036657 A1Published application
Methods for purifying viruses
OwnerJohn Chu-Tay Tang, Gary Vellekamp +1inventors
InventorsJohn Chu-Tay Tang, Gary Vellekamp, Laureano L. Bondoc JR.
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Abstract
The invention provides methods for purifying a virus from impurities in an aqueous medium.
Claims13
A method for purification of a virus preparation comprising:
- a) subjecting the virus preparation to anion-exchange chromatography, wherein the virus is eluted from an anion-exchange chromatographic medium;
- and
- b) subjecting the virus product of step A to size exclusion chromatography, wherein the virus is eluted from a size exclusion chromatographic medium.
Dependencies are inferred from the claim text.