Immortalized avian cell lines
AssigneeMerial Limited
InventorsJean-Francois Bouquet, Miloud Benchaibi, Jacques Samarut, Philippe Desmettre
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Abstract
The invention features non-transformant immortal avian cells, in particular derived from avian tissues, i.e., other than blood or hematopoietic cells, particularly fibroblasts and epithelial cells, for instance of embryos. The avian cells are immortalized by the SV40 T+t gene in the dependence of the MTI promoter. In particular they integrate the pDAMT vector.
Claims9
A method for producing viruses comprising producing viruses on an avian cell line comprising avian embryonic fibroblast cells and their progeny which are immortalized, but untransformed and which comprise, in their genome, the SV40 T+t gene.
Dependencies are inferred from the claim text.