Carnosic acid derivatives for promoting synthesis of nerve growth factor
AssigneeNagase & Co., Ltd.
InventorsKunio Kosaka, Toshitsugu Miyazaki, Toshio Yokoi
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Abstract
A novel carnosic acid derivative for promoting the synthesis of nerve growth factor (NGF), a composition comprising the carnosic acid derivative as an effective ingredient, as well as, a method of promoting the synthesis of NGF comprising administering an effective amount of the carnosic acid derivative as an effective ingredient to a subject requiring such promotion. The carnosic acid derivative, composition and method according to the present invention can safely and efficiently promote the production of NGF in the living body, without being accompanied by a side effect such as a loss of a quantitative balance of hormones in the living body.
Claims5
A carnosic acid derivative of the general formula (I):
- 6
- wherein R1 is a hydrogen atom or a C1-C5 alkyl group, and R2 and R3 independently of one another are a hydrogen atom, a C1-C5 alkyl group or a C1-C5 acyl group,
- provided that at least one of R1, R2 and R3 is not a hydrogen atom.
Dependencies are inferred from the claim text.