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US 2001/0034359 A1Published application
Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies
AssigneeExocell, Inc.
InventorMargo P. Cohen
Life of this patent
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Abstract
The present invention is directed to compositions that inhibit the nonenzymatic glycation of albumin, as well as methods of using compounds that inhibit albumin glycation for the treatment of glycation-related pathologies.
Claims22
A compound that inhibits the formation of glucose adducts on albumin.
A compound selected from those having the following structure:
- 9
- wherein:
- R′3, R′4, R′5, R′6, R2, R3, R4, R5, and R6, are the same or different and are hydrogen, chlorine, bromine, fluorine, iodine, methyl, ethoxy, methoxy, hydroxy, phosphate, sulfate, nitrate, amino or ethyl;
- X is hydrogen, sodium, potassium, or lithium.
1 more element
Dependencies are inferred from the claim text.