Methods of adminstering an ampa receptor antagonist to treat dyskinesias associated with dopamine agonist therapy
OwnerJ.Timothy Greenamyre, Bertrand L. Chenard +2inventors
InventorsJ.TIMOTHY GREENAMYRE, BERTRAND L. CHENARD, WILLARD M. WELCH, FRANK S. MENNITI
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Abstract
The invention relates to a method of treating dyskinesias associated with dopamine agonist therapy in a mammal which comprises administering to said mammal an effective amount of an antagonist of the AMPA receptor. Dopamine agonist therapy, as referred to in the present invention, is generally used in the treatment of a central nervous system disorder such as Parkinson's disease.
Claims8
A method of treating dyskinesia associated with dopamine agonist therapy in a mammal which comprises administering to said mammal an amount of an AMPA receptor antagonist that is effective in treating said dyskinesia.
A method of treating dyskinesia associated with dopamine agonist therapy in a mammal which comprises administering to said mammal an AMPA receptor antagonizing effective amount of a compound that is an antagonist of the AMPA receptor or a pharmaceutically acceptable salt of said compound.
Dependencies are inferred from the claim text.