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AssigneeIA, Inc.
InventorsJudith Louise Erb, Nallaperumal Chidambaram, James Germain Downward IV
Estimating the term…
A testing apparatus 10 having an absorbent matrix 12, including a membrane 14 which contains a plurality of counter-ions 16. Chromionophore (or fluorionophore)s 18 and affinophores 22 compete to carry ions into the membrane 14 and neutralize the charge of the counterions 16. Biological recognition molecules 42 bind to a portion of the affinophores 22 and prevent them from entering the membrane 14, thereby allowing more chromionophore (or fluorionophore)s 18 to enter the membrane 14. The portion of affinophores 22 bound to the biological recognition molecules 42 is inversely proportional to the amount or concentration of analyte 40 occurring within the solution or medium 30. The result of this is that the color of the membrane-covered matrix changes in a manner related to the concentration of the analyte. One application of this apparatus is a strip test for prediction of ovulation.
A test apparatus comprising an absorbent matrix onto which is placed in intimate contact a lipophilic membrane solution containing a plurality of molecules from the groups of chemicals comprising:
A test apparatus comprising an absorbent matrix onto which is placed in intimate contact a lipophilic membrane solution containing a plurality of molecules from the groups of chemicals comprising:
A test apparatus comprising an absorbent matrix onto which is placed in intimate contact a lipophilic membrane solution containing a plurality of molecules from the groups of chemicals comprising:
A test apparatus comprising an absorbent matrix onto which is placed in intimate contact a lipophilic membrane solution containing a plurality of molecules from the groups of chemicals comprising:
A method of semi-qualification in which the point of transition between two color regions on a test matrix is compared with a calibration scale which correlates the position of the transition with the concentration of the analyte.
An apparatus to determine the concentration of a certain metabolite occurring within a solution comprising:
An apparatus for determining the concentration of a certain metabolite occurring within a solution, said apparatus comprising;
A method to determine the concentration of a certain metabolite occurring within a solution, said method comprising the steps of:
The molecule [2-dodecyl-2-methyl-1,3-propanediyl bis[N-5′-amidoestrone-3-glucuronidyl-(benzo-15-crown-5)-4′-yl]carbamate]] shown in FIG. 6, which may be used as an affinophore for estrone-3-glucuronide assay in any instrumental context requiring such an affinophore including without limitation a strip test as described in this application, an affinophore based fiber optic sensor for estrone3-glucuoronide and/or an affinophore based electrode for estrone-3-glucuronide.
Dependencies are inferred from the claim text.