Transdermal drug patch
OwnerJie Zhanginventor
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Abstract
The present invention is directed toward a formulation for supplying additional drug for delivery in a transdermal drug delivery device. The invention comprises a drug, such as fentanyl that is capable of transdermal delivery, and a solution having a pre-designed solubility for the drug. The solution dissolves only a portion of said drug and allows a significant portion of the drug to remain undissolved in solution, thus providing extra drug to be delivered at a consistent, controlled delivery rate. The invention may used in conjunction with controlled heat.
Claims43
A formulation for supplying additional drug in a transdermal drug delivery device comprising:
- a drug, and
- a solution having a pre-designed solubility to dissolve only a portion of said drug to provide a controlled delivery rate.
A formulation for supplying additional drug in a transdermal drug delivery device comprising:
- a drug, and
- a solution having a first portion of said drug dissolved in said solution and a second portion of said drug being initially undissolved in said solution, said second portion being subsequently dissolved by controlled heating.
The formulation for providing transdermal drug delivery at a consistent rate comprising:
- a drug, said drug being capable of transdermal absorption,
- a solvent, said solvent having a predesigned solubility such that said drug formulation has a substantially constant concentration of dissolved drug, when excess amount of said drug is present in said formulation.
Dependencies are inferred from the claim text.