Method and computer program product for assessing neurological conditions and treatments using evoked response potentials
AssigneeThuris Corporation
InventorRichard Granger
Life of this patent
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AssigneeThuris Corporation
InventorRichard Granger
Estimating the term…
A method is provided for diagnosing the presence of a neurological disorder or otherwise assessing the neurological condition of a patient. The method also allows the assessment of a treatment regimen used by a patient. The method includes the collection and analysis of ERP data. The method of the invention begins by conducting a plurality of ERP trials on a patient. In an embodiment of the invention, the data from the ERP trials is then characterized to produce a characterizing ERP signal vector for the patient. Projections based on the characterizing ERP signal vector are then generated. The projections are compared to information derived from the ERP data of patients having known neurological conditions. To perform diagnosis, the projections are compared to standards, such as one or more characterizing ERP signal vectors from known healthy patients, and one or more characterizing ERP signal vectors from patients known to have the disorder. The probable presence or absence of the neurological disorder is decided by a weighted vote of the projections, where the weighting is a function of how closely each projection compares to the respective standards. Projections can also be used to perform other types of neurological assessment, such as tracking a patient's response to a treatment regimen, assessing the treatability of a patient with respect to a particular regimen, determining the effects of a particular regimen, or categorizing a patient in order to create a homogenous group for a clinical trial.
A method of facilitating the diagnosis of a neurological disorder, comprising the steps of:
A computer program product comprising a computer usable medium having computer readable program code means embodied in the medium for causing an application program to execute on a computer that facilitates the diagnosis of a neurological disorder, the computer readable program code means comprising:
A method of facilitating determination of treatability, with respect to a first treatment regimen, of a patient under assessment, the method comprising the steps of:
A computer program product comprising a computer usable medium having computer readable program code means embodied in the medium for causing an application program to execute on a computer that facilitates the assessment of the likely responsiveness of a patient under assessment to a treatment regimen, the computer readable program code means comprising:
A method of monitoring the response, to a treatment regimen, of a patient being treated for a neurological disorder, the method comprising the steps of:
A computer program product comprising a computer usable medium having computer readable code means embodied in the medium for causing an application program to execute on a computer that facilitates the assessment of a current condition of a patient being treated for a neurological disorder after beginning a treatment regimen, the computer readable code means comprising:
A method of assessing a patient with respect to the nature and extent of side effects experienced in response to a treatment regimen, wherein the patient is being treated for a neurological disorder, the method comprising the steps of:
A computer program product comprising a computer usable medium having computer readable program code means embodied in the medium for causing an application program to execute on a computer that facilitates the assessment of the nature and extent of side affects resulting from a treatment regimen, the computer readable program code means comprising:
A method of assessing the results of a treatment regimen for a neurological disorder, comprising the steps of:
A computer program product comprising a computer usable medium having computer readable program code means embodied in the medium for causing an application program to execute on a computer that facilitates the assessment of the results of a treatment regimen for a neurological disorder, the computer readable program code means comprising:
A method of determining an enrollment of subjects in a study of a neurological treatment, comprising the steps of:
A computer program product comprising a computer-usable medium having computer-readable program code means embodied in the medium for causing an application program to execute on a computer that facilitates the determination of enrollment of subjects in a study of a neurological treatment, the computer-readable program code means comprising:
Dependencies are inferred from the claim text.