Agents for treating neurodegenerative disorders

Use of the hydrogenated pyrido [4,3-b] indole derivatives of the formula (I) 5

• wherein
• R1 is Me, Et or PhCH2;
• R2 is H, PhCH2 or 6-Me-3-Py-(CH2)2;
• R3 is H, Me or Br;
• provided that
• (a) when +E,uns - - - represents a single bond, then
• R1=R3=Me;
• R2=H;
• and the compound is in the form of a cis (±) isomer;
• or
• (b) when +E,uns - - - represents a double bond, then
• (i) R1=Et or PhCH2, R2=R3=H,
• (ii) R1=R3=Me, R2=PhCH2,
• (iii) R1=Me, R2=6-Me-3-Py-(CH2)2, R3=H,
• (iv) R1=R3=Me, R2=6-Me-3-Py-(CH2)2,
• (v) R1=Me, R2=H, R3=H or Me,
• (vi) R1=Me, R2=H, R3=Br,
• and salts thereof with pharmacologically acceptable acids and quaternary derivatives as the agents for the treatment of neurodegenerative diseases.