# US 12,766,515 B2 · Well structures for biosensor devices > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,766,515 B2 - Document ID: US12766515B2 - Status: Granted - Kind: B2 - Application number: 18/362,753 - Filed: 2023-07-31 - Published: 2025-02-06 - Granted: 2026-10-20 - Earliest claimed: 2023-07-31 - Assignees: Analog Devices International Unlimited Company - Applicants: Analog Devices International Unlimited Company - Inventors: Christophe Antoine; Youri Victorovitch Ponomarev; Julie Byard - Web page: https://patentgrep.com/patent/US12766515B2 ## CPC - B01L 3/5085: {for multiple samples, e.g. microtitration plates} - B01L 2200/12: Specific details about manufacturing devices - B01L 2300/0636: Integrated biosensor, microarrays - B01L: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE ## Abstract A biosensor structure may include a well structure comprising a first well and a second well, wherein a geometry of the well structure impacts where a solution dispensed into the well structure is located. A biosensor structure may include an electrode configured to sense an analyte in the solution, the electrode disposed at a bottom of the well structure. A biosensor structure may include a membrane positioned on the electrode and on at least part of a bottom surface of the well structure. ## Claims ### Claim 1 A biosensor structure comprising: a well structure comprising a first well and a second well, wherein a geometry of the well structure impacts where a solution dispensed into the well structure is located, wherein the well structure comprises a surface including at least one of a nanostructure or a microstructure thereon to decrease adhesion of the solution, wherein the first well is disposed within the second well such that the first well and the second well extend to different depths relative to a surface of the substrate, wherein the second well has a greater diameter than the first well, and wherein the first well and the second well each comprise a respective tapered sidewall; an electrode configured to sense an analyte in the solution, the electrode disposed at a bottom of the well structure; and a membrane positioned on the electrode and on at least part of a bottom surface of the well structure. ### Claim 2 (depends on 1) The biosensor structure of claim 1, wherein at least part of the membrane is disposed directly on the bottom surface of the well structure. ### Claim 3 (depends on 1) The biosensor structure of claim 1, wherein the membrane is arranged such that a liquid in the biosensor structure can only reach the electrode by passing through the membrane. ### Claim 4 (depends on 1) The biosensor structure of claim 1, further comprising a second membrane, wherein the first membrane is within the first well, and wherein the second membrane is within the second well. ### Claim 5 (depends on 1) The biosensor structure of claim 1, wherein the well structure comprises a step extending from the tapered sidewall of the first well to the tapered sidewall of the second well. ### Claim 6 (depends on 1) The biosensor structure of claim 1, wherein the well structure comprises a first wall having a first height and a first width, and the first wall separates the first well and the second well. ### Claim 7 (depends on 6) The biosensor structure of claim 6, further comprising a second wall having a second height and a second width, the second wall defining an outer boundary of the second well. ### Claim 8 (depends on 7) The biosensor structure of claim 7, wherein the first wall is at a first distance from a center of the well structure, wherein the second well is at a second distance from the center of the well structure, wherein the second distance is greater than the first distance. ### Claim 9 (depends on 1) The biosensor structure of claim 1, wherein the electrode is an ion-selective electrode. ### Claim 10 (depends on 1) The biosensor structure of claim 1, wherein the first well and the second well are concentric. ### Claim 11 A biosensor structure comprising: a well structure comprising a first well and a second well, wherein the first well and the second well are stepped concentric wells, wherein the well structure comprises a surface including at least one of a nanostructure or a microstructure thereon to decrease adhesion of the solution, wherein the first well is disposed within the second well such that the first well and the second well extend to different depths relative to a surface of the substrate, wherein the second well has a greater diameter than the first well, and wherein the first well and the second well each comprise a respective tapered sidewall; an electrode configured to sense an analyte in a solution in the well structure; and a membrane positioned on the electrode. ### Claim 12 A biosensor structure comprising: a well structure comprising a first well, a second well, and a pillar disposed between the first well and the second well, wherein the well structure comprises a surface including at least one of a nanostructure or a microstructure thereon to decrease adhesion of the solution, wherein the first well is disposed within the second well such that the first well and the second well extend to different depths relative to a surface of the substrate, wherein the second well has a greater diameter than the first well, and wherein the first well and the second well each comprise a respective tapered sidewall; an electrode configured to sense an analyte in a solution in the well structure; and a membrane positioned on the electrode, wherein the first well and the second well are concentric, and wherein the second well surrounds the first well in plan view. ### Claim 13 (depends on 12) The biosensor structure of claim 12, wherein a height of the pillar is less than a total depth of the well structure.