Systems and methods for improved intensity determinations in mass analysis instruments

A method for performing mass analysis, the method comprising:

• ejecting, from a first well of a well plate, a first sample into a transport fluid;
• ionizing the first sample and the transport fluid to generate first ions;
• detecting the first ions over a first period of time;
• when a count rate of the detected first ions is above a background count rate threshold, accumulating a count of the detected first ions;
• storing the total accumulated count of first ions as an intensity for the first well of the well plate;
• ejecting, from a second well of the well plate, a second sample into the transport fluid;
• ionizing the second sample and the transport fluid to generate second ions;
• detecting the second ions over a second period of time;
• when a count rate of the detected second ions is above the background count rate threshold, accumulating a count of the detected second ions;
• and
• storing the total accumulated count of second ions as an intensity for the second well of the well plate,
• wherein the first time period is based on a time of ejection of the first sample and a time of ejection of the second sample.