Systems and methods to process electronic images to provide blur robustness

A system for processing electronic digital medical images, the system comprising:

• at least one memory storing instructions;
• and
• at least one processor configured to execute the instructions to perform operations comprising:
• receiving a plurality of electronic medical images of a medical specimen;
• dividing each of the plurality of electronic medical images into a plurality of tiles, each tile of the plurality of tiles being of a predetermined size;
• determining a plurality of sets of matching tiles, the tiles within each set corresponding to a given region of a plurality of regions of the medical specimen;
• for each tile of the plurality of sets of matching tiles, determining a blur score corresponding to a level of image blur of the tile;
• determining whether each tile within a first set of matching tiles has a blur score beyond a threshold value;
• upon determining that each tile within a first set of matching tiles has a blur score beyond a threshold value, applying at least one generative model to at least one tile of the first set of matching tiles to generate a higher resolution tile;
• for each set of the plurality of sets of matching tiles, determining a tile with the blur score indicating a lowest level of blur;
• determining a composite electronic medical image, the composite electronic medical image comprising a plurality of tiles, from each set of matching tiles, with the blur score indicating the lowest level of blur;
• and
• providing the composite electronic medical image for display.

A non-transitory computer-readable medium storing instructions that, when executed by a processor, perform operations processing electronic digital medical images, the operations comprising:

• receiving a plurality of electronic medical images of a medical specimen;
• dividing each of the plurality of electronic medical images into a plurality of tiles, each tile of the plurality of tiles being of a predetermined size;
• determining a plurality of sets of matching tiles, the tiles within each set corresponding to a given region of a plurality of regions of the medical specimen;
• for each tile of the plurality of sets of matching tiles, determining a blur score corresponding to a level of image blur of the tile;
• determining whether each tile within a first set of matching tiles has a blur score beyond a threshold value;
• upon determining that each tile within a first set of matching tiles has a blur score beyond a threshold value, applying at least one generative model to at least one tile of the first set of matching tiles to generate a higher resolution tile;
• for each set of the plurality of sets of matching tiles, determining a tile with the blur score indicating a lowest level of blur;
• determining a composite electronic medical image, the composite electronic medical image comprising a plurality of tiles, from each set of matching tiles, with the blur score indicating the lowest level of blur;
• and
• providing the composite electronic medical image for display.