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AssigneeTodd Pharm Co., Ltd.
InventorsSun-Shin Cha, Soo-Bong Park, Ye-Eun Jung, Da-Woon Bae, Bo-Gyeong Jeong, Bu-Gyeong Kang, Jung-hyun Lee, Hyung-Soon Yim, Kyeong Won Lee, Young Jun An
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The present application relates to a method of producing or purifying an FGF21 protein by using the heat-elasticity of FGF21. The method of producing or purifying the FGF21 protein according to an embodiment of the present application utilizes the heat stability and heat-elasticity of the FGF21 protein that is not denatured or precipitated even upon heat treatment and returns to the original structure when re-cooled after heat treatment, resulting in advantages of improving efficiency by simplifying a protein production process.
A method of producing an FGF21 protein, the method comprising:
A method of purifying an FGF21 protein, the method comprising heating a mixture containing an FGF21 protein and impurities at a temperature of 65° C. or higher.
Dependencies are inferred from the claim text.