Dynamic hydrogel and pulmonary fibrosis bionic chip
AssigneeAnivance AI Corporation
InventorsGuan-Yu Chen, Jia-Wei Yang, Chuan-Yi Yang
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Abstract
This invention provides a dynamic hydrogel that may deform in response to heat, the dynamic hydrogel is composed of a hydrogel composition and is obtained by crosslink reaction. The hydrogel composition includes photo initiator, PNIPAM, GelMA and annealed graphene oxide. Based on the weight of the hydrogel composition being 100 wt %, the content of the annealed graphene oxide is between 0.03 wt % to 0.15 wt % and the XPS absorption intensity ratio of sp2-C and sp3-C (sp2-C/sp3-C) is greater than 1. Meanwhile, this invention also provides a pulmonary fibrosis bionic chip containing the dynamic hydrogel.
Claims9
A dynamic hydrogel deforming in response to heat, comprising:
- a hydrogel composition obtained by photo-crosslinking, comprising:
- a photoinitiator;
- poly (N-isopropyl acrylamide);
- gelatin methacryloyl;
- and
- annealed graphene oxide,
- wherein based on a weight percentage of 100 wt % of the hydrogel composition, the annealed graphene oxide is present in an amount ranging from 0.03 wt % to 0.15 wt %, and the X-ray photoelectron spectroscopy absorption intensity ratio of sp2-C to sp3-C (sp2-C/sp3-C) of the annealed graphene oxide is greater than 1.
Dependencies are inferred from the claim text.