Solvent-free liquid from regenerated silk fibroin: a writeable and shapeable material
AssigneeIndian Institute of Technology Bombay
InventorsKamendra P. Sharma, Raj Kumar
Life of this patent
Estimating the term…
Abstract
The present invention provides a solvent-free viscoelastic RSF liquid by modifying the RSF surface with polyethylenimine and polyethylene glycol-based polymer surfactant, which surrounds each RSF molecule by forming a dual shell and thereby minimizes the inter RSF interactions and thus prevents formation of β-sheet aggregation. The engineering of RSF surface with PEI and PS significantly improved the conformational stability and storage time of RSF liquid compared to native RSF as silk I conformation of RSF liquid remained intact for more than 8 months.
Claims9
A viscoeastic RSF silk liquid comprising 6 wt % of RSF and a combination of oppositely charged polymeric species, wherein the oppositely charged polymeric species are 15 wt % of polyethyleneimine (PEI) and 77 wt % of poly (ethylene glycol)-based polymer surfactant (PS).
Dependencies are inferred from the claim text.