Anti-glycan antibody and use thereof

An antibody or a fragment thereof, which specifically binds to a 6-sulfosialyl Lewis X glycan, where the binding requires fucose, a sulfate group, and a sialic acid that form the 6-sulfosialyl Lewis X glycan, wherein the antibody or the fragment thereof comprises:

• a heavy chain variable region comprising the following CDRs:
• (a) CDRH1 comprising the amino acid sequence represented by SEQ ID NO:
• 1;
• (b) CDRH2 comprising the amino acid sequence represented by SEQ ID NO:
• 2;
• and
• (c) CDRH3 comprising the amino acid sequence represented by SEQ ID NO:
• 3;
• and
• a light chain variable region comprising the following CDRs:
• (d) CDRL1 comprising the amino acid sequence represented by SEQ ID NO:
• 4;
• (e) CDRL2 comprising the amino acid sequence represented by SEQ ID NO:
• 5;
• and
• (f) CDRL3 comprising the amino acid sequence represented by SEQ ID NO:
• 6.