Method for purifying sucralose
AssigneeAnhui Jinhe Industrial Co., Ltd.
InventorsZhenghua Li, Jiaxin Xia, Chuanjiu Xu, Guojia Xu
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Abstract
Disclosed is a method for purifying sucralose, including: removing a solvent from a sucralose reaction solution to obtain a concentrated crude sucralose solution; under stirring, adding ethyl acetate into the concentrated crude sucralose solution, heating to a preset temperature, and holding at the preset temperature for a first preset time to obtain a crude product slurry with a certain amount of a sucralose crystal; and subjecting the crude product slurry to gradient cooling to an endpoint temperature, holding at the endpoint temperature for a second preset time, and filtering to obtain a sucralose crystal.
Claims7
A method for purifying sucralose, comprising:
- removing a solvent from a sucralose reaction solution to obtain a concentrated crude sucralose solution;
- under stirring, adding ethyl acetate into the concentrated crude sucralose solution, heating to a preset temperature, and holding at the preset temperature for a first preset time to obtain a crude product slurry containing sucralose crystal;
- and
- under stirring, subjecting the crude product slurry to gradient cooling to an endpoint temperature, holding at the endpoint temperature for a second preset time, and filtering to obtain the sucralose crystal;
- wherein
- the preset temperature is in a range of 45° C. to 65° C.,
- the first preset time is in a range of 0.5 h to 3 h,
- the gradient cooling is conducted as follows:
- cooling the crude product slurry to the endpoint temperature at a cooling rate of 1° C./10 min to 3° C./10 min, and the endpoint temperature is in a range of 0° C. to 10° C., and
- the second preset time is in a range of 0.5 h to 3 h.
Dependencies are inferred from the claim text.