Polyhydroxy multi-ionic compounds and methods of making and use thereof

A polyhydroxy multi-ionic compound having the structure of formula (V) or (VII):

• wherein:
• l, m, n, o, and p are independently an integer of 0-1000, and wherein at least one of l, m, n, o, and/or p is an integer of 1-1000;
• X is —(CH2)m1—, —(Ar)—, —(CH2Ar)n1—, —((CH2)o1Ar(CH2)o1)p1—, —((CH2)q(NH(CH2)q)r—, or —(CH2NDCH2)s—, wherein D is H,
• wherein m1, n1, o1, and q are independently an integer from 0 to 10 and p1, r, and s are independently an integer from 1 to 100;
• X1 is NH or O;
• R1 is H, CH3, or an unsubstituted, linear or branched C2-C10 alkyl group;
• M is absent or an unsubstituted, linear C1-C30 alkylene group;
• Z is —NR3R4R5(+) Y(−), —COOH, —SO3H, —PO3H2, or a salt thereof;
• and
• R3, R4 and R5 are independently C1-C10 alkyl group or benzyl group.