# US 12,759,763 B1 · Tamper evident integrated closure > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,759,763 B1 - Document ID: US12759763B1 - Status: Granted - Kind: B1 - Application number: 19/020,773 - Filed: 2025-01-14 - Granted: 2026-10-13 - Earliest claimed: 2021-10-04 - Assignees: Medical Device Engineering, LLC. - Applicants: Patrick Vitello; Panagiotis Peter Vassios - Inventors: Patrick Vitello; Panagiotis Peter Vassios - Web page: https://patentgrep.com/patent/US12759763B1 ## CPC - B65D 41/46: Snap-on caps or cap-like covers - B65D 47/125: {Caps with bayonet cams} - B65D 47/18: for discharging drops; Droppers (droppers in general B01L3/00; {pipettes connected to container closures B01L3/0282}) - B65D 2401/15: Tearable part of the closure (B65D2401/60 takes precedence) - B65D: CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES ## Abstract A closure for a medical solution containing bottle, wherein the closure includes a cap having a shroud operatively disposed in closing relation to the bottle neck and/or access opening of the bottle. The cap is removably connected to the bottle in the closing relation and may include a shrouded tamper evident indicator member and/or an integrated cap and spout construction. As practically applied, the indicator member is connected to an interior surface of shroud, at least initially inwardly of an open end of thereof in a non-visually observable location. Upon removal of the cap from the bottle and replacement thereof, at least a portion of the indicator member will be disposed exteriorly of the shroud in a visually observable location on the bottle. The closure may also include a spout integrated into the cap. ## Claims ### Claim 1 A closure for a medical solution containing bottle, said closure comprising: a cap including a shroud, said shroud having an open-end, said cap removably connected to the bottle in a closing relation thereto an indicator member connected to an interior surface of said shroud inwardly of said open-end, in a non-observable location, said indicator member including a base and an indicator segment, said indicator segment removably connected to said base, said indicator member connected to the bottle concurrent to said closing relation of said cap, and said indicator segment detachable from said base and disposed on a bottle neck exteriorly of said shroud, concurrent to a removal of said cap from the bottle. ### Claim 2 (depends on 1) The closure as recited in claim 1 wherein said indicator segment is disposed in a visually observable location on the bottle neck, concurrent to a detachment thereof from said base and said removal of said cap from the bottle. ### Claim 3 (depends on 2) The closure as recited in claim 2 wherein said indicator segment is disposed in a visually observable location on the bottle neck, concurrent to said detachment thereof and concurrent to a replacement of said cap in the said closing relation. ### Claim 4 (depends on 1) The closure as recited in claim 1 wherein said indicator segment is disposed in a visually observable location on the bottle neck, concurrent to a detachment thereof from said base and concurrent to a replacement of said cap in the said closing relation. ### Claim 5 (depends on 1) The closure as recited in claim 1 further comprising a frangible structure disposed in interconnecting relation between said base and said indicator segment. ### Claim 6 (depends on 5) The closure as recited in claim 5 wherein said frangible structure comprises a plurality of frangible segments disposed in spaced relation to one another along a co-extending the length of said base and said indicator segment. ### Claim 7 (depends on 6) The closure as recited in claim 6 wherein said indicator member comprises an annular configuration disposed in surrounding relation to the bottle neck, concurrent to said closing relation of said cap. ### Claim 8 (depends on 1) The closure as recited in claim 1 wherein said indicator member is cooperatively structured with the bottle neck to define a snap-fit connection therewith. ### Claim 9 (depends on 8) The closure as recited in claim 8 wherein said cooperative structure of said indicator member comprises an at least partially a flexible, frangible interconnection of said indicator segment to said base. ### Claim 10 (depends on 1) The closure as recited in claim 1 further comprising a spout including a flow channel formed therein, said flow channel disposed in fluid communication with an interior of the bottle, via a bottle access opening, concurrent to said spout connected to the bottle. ### Claim 11 (depends on 10) The closure as recited in claim 10 wherein said spout is at least partially disposed within the bottle access opening concurrent to said spout connected to the bottle. ### Claim 12 (depends on 10) The closure as recited in claim 10 wherein said flow channel is dimensioned and configured to define a droplet dispensing of the medical solution from the bottle. ### Claim 13 (depends on 10) The closure as recited in claim 10 wherein said spout is integrated into said cap in a fixed, removable connection therewith, said spout movable with said cap into said closing relation of said cap to the bottle. ### Claim 14 (depends on 13) The closure as recited in claim 13 wherein said spout includes an inner segment and an outer segment, said flow channel formed in said outer segment in fluid communication with an interior of said inner segment. ### Claim 15 (depends on 14) The closure as recited in claim 14 wherein said inner segment is disposed into and through the bottle access opening concurrent to said spout connected to the bottle. ### Claim 16 (depends on 13) The closure as recited in claim 13 wherein said inner segment is disposed in inwardly spaced relation to an inner surface of said shroud, concurrent to said fixed, removable connection with said cap. ### Claim 17 (depends on 16) The closure as recited in claim 16 further comprising a connector structure formed on said interior surface of said cap in spaced relation to said inner segment. ### Claim 18 (depends on 17) The closure as recited in claim 17 wherein said connector structure is cooperatively disposed and configured with the bottle neck to define a removable, threaded attachment therebetween concurrent to said closing relation of said cap to the bottle. ### Claim 19 (depends on 13) The closure as recited in claim 13 wherein said fixed, removable connection of said spout with said cap comprises a frictional engagement of an exterior surface of said spout with an interior surface of said cap. ### Claim 20 (depends on 19) The closure as recited in claim 19 wherein said spout comprises at least one outwardly extending surface portion disposed in said frictional engagement with said interior surface of said cap.